Associate Scientist Bioscience

Description

Summary:

• The position resides in the Critical Pipeline Reagent Sciences Group (CPRS) contained within the Purification Process Sciences R&D department.
• Members of the CPRS function work closely with the research scientists and process development scientists to generate pipeline supporting molecules.
• Position may require weekend work and/or periodic late-nights.

Main duties are as follows:

• Generation of biopharmaceutical reagents to advance the R&D Client pipeline
• Performing purifications for complex biopharmaceutical drugs such as antibodies, bispecific antibodies, fusion proteins, DuetMabs, pDNA, and viruses
• Performing conjugations of candidate drugs and anti-IDs to support PK/PD studies
• Solving challenging protein purification problems
• Performs technology development projects to increase purification efficiency
• Coordinating closely with the research department, cell culture group, and analytical biotechnology group in order to meet project timelines and company goals
• Analyzing and interpreting analytical and process data
• Maintain accurate records of data and actively participate in laboratory organization
• Professionally deliver results to internal and external audiences
• Supervision: Should be able to function with limited supervision and is expected to work independently on a day-to-day basis. Expectation for independence will increase with time and experience in the position.

Desired Skills:

• Highly team-oriented, energetic, critical thinker, organized, capable of multitasking with excellent oral and written skills
• Knowledge of Basic Protein Chemistry, Protein Chromatography, Purification Process Design for Monoclonal Antibodies and Novel Proteins, Basic Analytical Techniques (HPLC and SDS-PAGE Analyses), Protein Modification by Conjugation, Statistics Software and DOE Analysis
• Experience performing protein chromatography using Akta/Akta software
• Experience performing analytical testing