Pharmacologist

Description

Fully onsite

• Based in MetroWest (Boston area); location is train-accessible
• Local candidates preferred, but open to those willing to relocate at their own expense
• Paid parking required
• Collaborative team of 5 researchers

Key Focus Areas :

• COPD and Respiratory Disease Models: Primary responsibility will be COPD studies in mice (~50% of workload), along with other respiratory disease models.
• Pharmacology Focus: Role involves working with pharmacological compounds in preclinical studies.

 Animal Work: Direct work with mice, including:

• Dosing (various methods), blood collection, tissue harvest
• Compound/reagent preparation

Must Have Experience:

• Master’s degree in a life science field with 2+ years of lab/research experience, or
• Bachelor’s degree with 2+ years of relevant experience in biotech, pharmaceutical, or research institutions.
• PhD candidate will be accepted, min 2+ years of experience.
• ELN and scientific record-keeping o Animal handling and dosing techniques
• Blood and tissue collection methods
• COPD and Respiratory Disease Models
• Preferred: Smoke exposure for COPD models/ Lung function assessments

About the Job:

• We are seeking a highly motivated in-vivo pharmacologist to join the Type 2 Immunology Cluster within the Immunology and Inflammation Therapeutic Area located in Cambridge, MA.
• The ideal candidate will possess a strong background in in-vivo pharmacology, contributing technical skills and functional knowledge.
• The candidate will also be involved in the design, overall conduct, and the reporting of in-vivo pharmacology study results to project teams.
• The position is a hands-on, laboratory-based role that requires strong communication skills, attention to detail, a results-driven way of working, and ability to work both individually and in a team environment, and to work across functions.
• A successful candidate is expected to analyze, record and report data, be able to develop and learn new techniques, and be able to multi-task between multiple projects.

Main Responsibilities:

• Responsible for designing and performing in-vivo pharmacology experiments in support of project team goals. This includes study design, data collection and recording, communication of results, and report writing.
• Summarize and present study data to project teams within established timelines.
• Generate specific pharmacology reports based on studies performed to support IND submission.
• Capacity to use established procedures and methodologies with the ability to transform novel approaches into routine practice.
• Must be a technical contributor.
• Ability to troubleshoot experiments.
• Support the development of disease relevant in-vivo models.
• Must be well organized and detail oriented.
• Must have meticulous record keeping skills according to Client quality guidelines. Maintain a thorough and compliant laboratory notebook.
• Must adhere to all federal, local, and Client animal welfare guidelines.
• Must be capable of working alone and in a team environment.

Qualifications:

• Experience with in-vivo immunology models. Previous experience with models of respiratory disease, dermatitis models, and smoke induced COPD models is a plus.
• Ability to apply technical skills to complete assigned work as a competent technical contributor.
• Ability to design and perform in-vivo pharmacology experiments.
• Experience in various dosing methods, blood collection techniques, and tissue harvest are required.
• Experience with compound or reagent preparation.
• Ability to work under moderate supervision with regular review of results and methods utilized.
• Ability to present study related results to project teams.
• Proven ability to work in a dynamic, customer-focused and results-oriented environment.

Education and Experience:

• Master’s Degree plus a minimum of 0 to 3 years of relevant research experience in a biopharmaceutical setting OR a Bachelor’s Degree plus a minimum of 2 to 5 years of relevant research experience in a biopharmaceutical setting.