Proteomics Bench Scientist

Description

Work schedule: Monday - Friday / First shift flex

 Note:

• Preferred PhD candidates
• Must have minimal MA + 5 years exp

Position Summary

• Candidate will be responsible for developing proteomics workflows using advanced high-resolution mass spectrometry techniques.
• Key duties include development and optimization of sample preparation methods from cell lines and other matrices for mass spectrometry analysis and data processing with various bioinformatics tools; collaborative work with colleagues; accurately documenting all activities in an electronic lab notebook (ELN).
• This role requires expertise in LC-MS based proteomics.
• Experience with cell culture and cell manipulation is a plus.

Position Responsibilities

• Applying knowledge of proteomics workflows to develop and implement optimal strategies for the preparation and analysis of cellular samples
• Working collaboratively with experts in the team to advance innovative proteomics strategies
• Employing different bioinformatics tools for data analysis and fitting
• Consistent record keeping using an electronic lab notebook (ELN)

Organizational Relationships

• This hire will interact daily with the managers and 3-4 colleagues in the cross-functional team for method development, laboratory work prioritization, experiment planning and execution. The hire might also work on common assignments with colleagues in a larger bioanalytical group at the same location, as needed.
• The hire will participate in bi-weekly group meetings and other team meetings and discussions, as relevant to their work.

Education And Experience

• M.Sc 5+ years, PhD 0+ years in a relevant scientific field with a documented experience in proteomics and mass-spectrometry

Technical Skills Requirements

Required:

• Advanced knowledge and documented expertise with mass-spectrometry based proteomics approaches: label- or label-free quantification (TMT or DIA)
• Experience with high-resolution mass-spectrometry instruments, such as Orbitraps and timsTOF
• Experience with sample preparation based on enrichment (incl. affinity purification), and universal protein extraction
• Bioinformatics skills relevant for mass-spec data search, statistical analysis and visualization
• Preferable:
• Experience with membrane protein analysis and/or cell surface proteomics
• Knowledge of cell culture techniques and experience conducitng cell-based assays

Physical Position Requirements

• Walking, taking the stairs, standing, sitting as appropriate for a laboratory-based position