Research Associate

Description

Specific Responsibilities:

• The in vivo Antibody Discovery group is a specialized team within the Protein Therapeutics function that is responsible for the discovery and optimization of biological drug candidates.
• We are seeking a highly motivated contingent worker to join this team, with grade level corresponding to Research Associate to Associate Scientist.
• This is a limited term (6-month) position, with possibility being extended or converted into full time permanent employee.
• The successful candidate will contribute to antibody discovery efforts as part of a cross-functional team specializing in the discovery and screening of novel biologic modalities in support of all therapeutic areas at Client.

Job Responsibilities:

• In this laboratory-based role, the successful candidate will support efforts to generate novel antibody-based therapeutics.
• Ideally, the applicant has a strong foundation in molecular biology, PCR, in vitro mRNA production, and molecular cloning
• Drive antibody discovery by antibody sequencing/cloning, reformatting, and initial characterization.
• Design and optimize DNA constructs for in vitro mRNA immunogen production.
• Independently design, analyze and interpret experiments for the discovery and characterization of the isolated antibodies and alternate binder formats.
• Collaborate with Research Data Sciences and Discovery Sciences & Technology colleagues to support NGS-based antibody discovery and functional characterization.
• Present scientific results in multiple settings and attend project team meetings.
• Deliver scientific results for publications, patents, and regulatory submissions.

Qualifications:

• B.S. in biological sciences, preferably with minimum 2 years of relevant professional experience or M.S. with minimum 1 years of experience and a proven track record in molecular biology and preferably antibody discovery.

An ideal candidate will have experience in most of the following areas:

• Strong expertise in molecular biology (PCR, reverse transcription, cloning) is required. Experience with mRNA immunogen production is a plus.
• Experience in single-cell FACS sorting is desired.
• Working knowledge in other single-cell technologies a plus.
• Mammalian cell culture and transient protein expression experience is a plus.
• Highly organized and capable to track multiple, complex workflows.
• Strong written and oral communication skills, with an ability to work in a dynamic, collaborative, and evolving environment.