Jobs

Description

 This is an on-site laboratory role.

Daily Schedule: Monday - Friday / First Shift

Candidates must be able to speak to true job experience.

What You Will Achieve

• Manufacturing Sciences and Technology (MSAT) Upstream Group at Client is looking for a highly motivated and versatile candidate to join our multidisciplinary team of scientists and engineers in Andover, MA. MSAT supports Client’s portfolio of late-stage development of commercial biopharmaceuticals and vaccines, and is responsible for process troubleshooting, process improvements and second- generation process development.
• We are looking for someone who is eager to contribute independent thinking and technical excellence to the upstream fermentation team.
• The Scientist will be a part of a diverse and motivated team of scientists, engineers, and technical professionals that are focused on fermentation processes to produce biotherapeutics.
• The role is well-integrated into the rest of the MSAT Microbial Team.
• This role will collaborate with other MSAT scientists to setup bioreactors and execute well-designed experiments, including but not limited to basic analytics, data acquisition and documentation of work.
• The candidate would also be responsible for user-level maintenance of the relevant equipment and associated documentation.

How You Will Achieve It

Role Responsibilities

• Plan and execute upstream process experiments at benchtop scales
• Participates and significantly contributes to discussions in lab and project team meetings on design of experiments (bioreactor and shake flask) and interpretation of experimental data.
• Acts as a technical resource within the upstream group. Provides formal/informal mentoring to junior colleagues within work group/project team.
• Works under limited supervision with periodic review of achievement of results and experimental approaches employed. Manages own time to meet agreed targets. Develops plans for short-term work activities on own projects.
• Ensures effective, high-quality, timely and appropriate documentation in electronic laboratory notebooks and internal technical reports; presents data/ strategy to scientists and management in appropriate internal and external venues (technical meetings, project team meetings, conferences) as appropriate.
• Contributes to safe, efficient, effective and harmonious lab environment, ensures appropriate cleanliness and status/ operability of shared or assigned lab space or equipment; strong lab citizen and collaborative team player; approaches the job with energy and commitment; frequently demonstrates initiative.
• Participate in multi-disciplinary teams to resolve complex issues
• Assist in manufacturing investigations and process troubleshooting
• Assist on process improvement projects

Qualifications

Required

• Ph. D. with 0-4 years of experience in biotechnology Master’s degree in a relevant discipline with at 3-5 years of applicable bioprocess experience or bachelor’s degree with at least 7 years of experience
• Proficient in aseptic technique (required)
• Proficient in benchtop bioreactor operation and associated analytical tools (required)
• Experience with bench scale cell culture and/or bacterial fermentation (required)
• An in-depth knowledge of bioreactor operations fed-batch, perfusion, and continuous modes of cell culture
• Strong trouble-shooting skills and extreme attention to detail required
• Ability to troubleshoot technical issues, plan and carry out experiments independently, and work with complex instrumentation and software.
• Excellent oral and written communication skills.
• Strong analytical and computer skills.

Preferred

• Prior experience developing and maintaining scale down models of commercial biopharmaceutical processes
• Prior experience in developing commercially relevant cell culture processes to produce pharmacologically active proteins
• Experience with control and data acquisition systems
• Demonstrated experience developing or introducing new technology into commercial processes
• Knowledge of all aspects of cell culture/fermentation, including batch, fed-batch, perfusion and harvest/clarification operations
• Familiarity with DoE and other statistical tools
• Experience with processing and interpreting large data sets
• Familiarity with regulatory filings, cGMP requirements and operational constraints

Physical/Mental Requirements

• Involves typical bioprocessing lab activities
• Ability to routinely lift 50 lbs.
• Standing for prolonged periods of time, walking, bending, and using tools.
• Ability to perform mathematical calculations and ability to perform complex data analysis.

Non-Standard Work Schedule, Travel Or Environment Requirements

• Requires off hours working to support laboratory work on average of two times per week.