Senior Associate Scientist

Description

Position summary:

• We are seeking a senior associate scientist to help manage our internal protein inventory and assist with routine antibody purifications. Y
• our primary activities will be to fulfill inventory requests, perform FPLC-based antibody purifications, and analyze purified material to confirm quality.
• Your work will support the core protein production group within the Research department and will play a critical role in driving preclinical efforts to develop novel antibody-based therapeutics.

Position responsibilities:

• Regularly monitor, self-assign, and update inventory requests
• Use LIMS interface and Excel workbooks to fulfill and document assigned requests
• Manipulate protein samples under sterile conditions inside a biosafety cabinet
• Purify antibodies with AKTA Avant equipment
• Characterize purified proteins by UPLC, UV-vis, and Mass Spectrometry methods
• Maintain detailed records of purification experiments in an ELN
• Complete general lab upkeep including buffer preparation and basic FPLC/column maintenance
• Communicate activities to the team and troubleshoot any issues, elevating problems to management as needed

Organizational relationships:

• Regularly interact with members of Protein Solutions Group, particularly the Purification sub-team
• Regularly interact with inventory requestors, particularly members of the Conjugation and In Vivo groups

Education and experience:

• Bachelor’s degree in STEM field (e.g., Biology, Biochemistry, Chemistry) with 2+ years post-degree lab experience

Technical skills requirements:

• Wet lab experience using pipettes and maintaining sample sterility using biological safety cabinets
• Hands-on experience with FPLC protein purification
• High attention to detail and successfully accomplishes meticulous work
• Demonstrated ability to handle simultaneous responsibilities and adapt to changing priorities
• Able to identify concerns, investigate solutions and escalate to management
• Work in a team-based environment employing a solution-based approach
• (Preferred) experience with protein analytical methods (e.g., analytical SEC, HIC, mass spectrometry)
• (Preferred) experience keeping records in ELN systems
• (Preferred) writes or understands advanced Excel formulas and VBA or other coding languages

Physical position requirements:

• Able to lift and move 25 lbs

Hard Skills:

• Manipulate protein samples under sterile conditions inside a biosafety cabinet
• Regularly monitor, self-assign, and update inventory requests
• Purify antibodies with AKTA Avant equipment

Preferred Skills:

• Experience with protein analytical methods (e.g., analytical SEC, HIC, mass spectrometry)
• Experience keeping records in ELN systems
• Writes or understands advanced Excel formulas and VBA or other coding languages