Scientist

Description

Onsite

Schedule: 9a-5p flexibility in the scheduling for 8a-4p

Would like experienced candidate, prefer to not have candidates that are just out of undergrad.

• Role is lab based with a equal amounts of office work. (Lab book entries, Group meetings, Group presentations.)
• Needs Cell Culture experience in the lab
• Collaborative role, looking for 4+ years of experience developing complex assays.
• Office Culture: smaller groups, not typical industry role, which can be a perk as it is more intellectually stimulating.

Scientist (non PhD)—ADC Biology

ROLE SUMMARY

• As a Scientist (non-PhD) on our ADC Biology team, you will be a key driver in advancing next-generation ADC technologies through collaborative, cross-functional research that spans from early discovery to pre-clinical development.
• You will develop assays and execute screening and identification of novel chemotypes that function as payloads for antibody drug conjugates for cancer therapy.
• You will work collaboratively with chemistry and other cross functional teams to understand mechanism of action of identified payloads.
• You will analyze, interpret and communicate the data effectively to key stake holders.

KEY RESPONSIBILITIES

• Apply cellular, biochemical, immunological, and molecular biology laboratory techniques to preclinical research projects in the areas of Cancer signaling and Cancer biology
• Investigate MOAs of our therapeutics through development, optimization, and execution of complex assays
• Interact and collaborate with other functional groups across research
• Provide leadership within technical area of expertise; may train, direct or mentor others
• Design and execute key experiments to investigate novel therapeutic targets and MOAs of novel payloads to enable clear go/no-go decisions.
• Independently analyze data, document results, and present findings to large and small audiences
• Maintain rigorous records of experimental progress using electronic laboratory notebooks
• Present experimental results and scientific rationale to colleagues
• Execute molecular, biochemcial and cell-based methodologies including cytotoxicity assays, HiBit, HTRF, ELISA, western blotting, automated liquid handling multicolor flow cytometry, immunofluorescence and live cell microscopy.
• Aid in execution and analysis of additional experiments as need arises within the ADC discovery research team

MINIMUM REQUIREMENTS

• Bachelor's degree in Cellular or Molecular Biology, Immunology, Biochemistry or related field and 6+ years' relevant industry experience OR
• M.S. degree in Cellular or Molecular Biology, Immunology, Biochemistry or related field with 4+ years' relevant industry experience
• Experience with Microsoft Office (Excel, Word, PowerPoint) and analytical (Prism, FlowJo, etc.) software programs
• Experience designing, performing and interpreting complex experiments that require significant insight into problems being addressed with some guidance
• Working knowledge in specific areas of Cancer Biology and Cancer therapeutics esp, small molecule agents, Biologics and ADCs
• Experience working independently and working on multiple projects
• Experience collaborating across teams and a variety of disciplines to provide experimental expertise and support others on joint projects
• Experience leading parts of projects or initiatives within area of expertise
• Excellent written/oral communication skills with experience presenting/sharing details of the work with key stake holders

PREFERRED REQUIREMENTS

• Experience in experimental cancer biology, biochemical and/or immunological techniques (e.g., Cell culture, cytotoxicity assays, HiBit, HTRF, ELISA, western blotting, automated liquid handling multicolor flow cytometry, immunofluorescent and live cell microscopy.).
• Background knowledge of the field of cell signaling and biochemistry
• Experience developing complex cell and biochemical assays