Bioanalytical Scientist

Description

100% onsite

Years of experience/education and/or certifcations required:

• Someone with industry experience, fresh graduate would not be a good pick.

What are the top 3-5 skills, experience or education required for this position:

• Degree in chemistry, pharmacology or other related fields. BS with 5+ years or MS with 2+ years in a pharmaceutical industry setting with a focus on mass spectrometry. Prior industry experience in drug discovery/development is highly desired.
• Hands-on experience with QQQ (SCIEX) Mass Spectrometer is required, additional experience with qTOF (Agilent, Bruker, SCIEX) and/or Orbitrap (Thermo) mass spectrometers is a plus.
• Hands-on experience with biologics bioanalysis is highly desired, additional experience with oligonucleotide analysis is a plus.
• Hands-on experience with immuno-affinity purification and automation systems (e.g., TECAN, AssayMap Bravo or Hamilton) is highly desired.
• Highly motivated, self-driven and results-oriented with excellent communication and presentation skills; capable of working both as a team player and individual contributor.

What type of environment is this person working in?- Lab

Work Schedule (Define days,# of hours)/ Is Overtime offered or required? If yes, how many hours, what impact to scheduled working hours?

• Monday – Friday 9-5
• No OT offered or required.

Scientist, Biologics LCMS Bioanalysis, (6-month contractor)

The Client is seeking a highly motivated and energetic bioanalytical scientist to join the biologics bioanalysis, characterization and proteomics (BBCP) group.

• The primary responsibility of this position is to support LC-MS (liquid chromatography-mass spectrometry)-based bioanalysis and method development for biologic entities, such as monoclonal antibodies, multi-specific antibodies, antibody-drug conjugates (ADCs), and other novel modalities.
• The successful candidate will have experience in optimizing and implementing hybrid LC-MS-based bioanalytical methods to support non-regulated preclinical PK and TK studies.
• Responsibilities include routine sample preparation, method development, instrument maintenance, data analysis, report writing, and presenting data at internal and external meetings.

Key tasks and responsibilities:

• Perform affinity purification and digestion of biological therapeutics (including but not limited to monoclonal and bispecific antibodies, antibody drug conjugates, antibody-siRNA conjugates, and fusion proteins) from biological matrices manually or using automation systems.
• Operate and maintain LC/MS instruments to generate high-quality experimental data.
• Optimize and develop LC/MS methods to meet assay specificity and sensitivity requirements.
• Analyze data and maintain detailed, accurate and comprehensive study documentation in electronic laboratory notebooks.
• Communicate data interpretation internally and externally.

Qualifications:

• Degree in chemistry, pharmacology or other related fields. BS with 5+ years or MS with 2+ years in a pharmaceutical industry setting with a focus on mass spectrometry. Prior industry experience in drug discovery/development is highly desired.
• Highly motivated, self-driven and results-oriented with excellent communication and presentation skills; capable of working both as a team player and individual contributor.
• Hands-on experience with QQQ (SCIEX) is required, additional experience with qTOF (Agilent, Bruker, SCIEX) and/or Orbitrap (Thermo) mass spectrometers is a plus.
• Hands-on experience with biologics bioanalysis is highly desired, additional experience with oligonucleotide analysis is a plus.
• Hands-on experience with immuno-affinity purification and automation systems (e.g., TECAN, AssayMap Bravo or Hamilton) is highly desired.
• In-depth understanding of PK, TK and PK/PD studies is preferred.