Jobs

Description

Location: Santa Monica, CA (5 days)

Key responsibilities

• Culture, quality control (QC), and cell banking of diverse solid tumor cell lines
• Engineer, culture and characterize CAR T cell function in vitro
• Perform routine laboratory procedures including ddPCR, qPCR, Flow, Luminex/MSD for ELISA and various cell-based immunoassays and biochemical assays
• Analyze, interpret, and translate results into actionable and tangible findings
• Maintain accurate and detailed records of laboratory procedures, experimental designs, and results in compliance with organizational standards; familiarity with Benchling a plus.
• Design and execute fit-for-purpose or hypothesis-based experiments; analyze and
• interpret data to support development
• Communicate effectively research plans and results, in both oral and written form
• Coordinate tasks across multiple projects, work closely with cross-functional teams to support ongoing research projects, ensuring seamless integration of experimental findings
• Contribute to a dynamic, exciting culture that embraces teamwork and innovation
• Support the timeline-sensitive Pre-IND/IND research activity and work cross-functionally with different teams

Basic Qualifications

• Master’s Degree and 2+ years of related industry/academic Experience OR
• Bachelor’s Degree and 4+ years of related industry/academic experience OR

Preferred Qualifications

• BS 6+ years or MS 3+ years or equivalent degree of relevant experience in Cell Biology and/or Immunology.
• Prior hands-on experience in the CAR-T field is preferred.
• Proficiency in experiment design, data analysis, interpretation, and presentation. Required high degree of accuracy and attention to details.
• Hands on experience with primary T cell isolation, culture and assays (e.g. cytotoxicity assays, cell proliferation assays, xCELLigence/eSight assays), multicolor flow cytometry,
• SCLC cell line culture and data analysis (FACSDiva, FlowJo, GraphPad, Prism, Excel).
• Experience with ex vivo CAR T manufacturing is preferred
• Strong communication skills, both written and verbal.
• The ideal candidate should be flexible to meet team’s priorities and willing to support team members with their projects.